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Hydrogen Wettability Of Sandstone Reservoirs, Stefan Iglauer, Muhammad Ali, Alireza Keshavarz 2020 Edith Cowan University

Hydrogen Wettability Of Sandstone Reservoirs, Stefan Iglauer, Muhammad Ali, Alireza Keshavarz

Research Datasets

Data set include the data for contact angle data as a function of pressure, temperature and stearic acid concentration in H2. One exemplary figure is also provided for contact angle measurement in H2 atmosphere.


Download Bmp Trains 2020 Newest Version 4.2.3, Martin Wanielista 2020 University of Central Florida

Download Bmp Trains 2020 Newest Version 4.2.3, Martin Wanielista

BMP Trains

This is version 4.2.3 BMP Trains 2020. It is a computer program used to assess the average annual removal effectiveness of nutrients. It is based on research from the State of Florida and uses design criteria in the State. It is accepted by regulatory agencies in the State. It was posted for use stating on November 22, 2020.

This version allows for greater flexibility in media selection. Noted is the choice of treatment rate to calculated service life. Treatment rate is usually decreased by 2 to incorporate a factor of safety. It also increases the reporting decimal places ...


Transplantation Of Umbilical Cord Blood Mononuclear Cells Attenuates The Expression Of Il-1Β Via The Tlr4/Nf-Κb Pathway In Hypoxic-Ischemic Neonatal Rats, Meng-Bei Zhang, Chao-Chao Song, Guang-Zu Li, Lan-Fen Chen, Rui Ma, Xiao-He Yu, Ping Gong, Xiao-Li Wang 2020 Department of Medical Imaging, Weifang Medical University, Weifang 261053, Shandong, China

Transplantation Of Umbilical Cord Blood Mononuclear Cells Attenuates The Expression Of Il-1Β Via The Tlr4/Nf-Κb Pathway In Hypoxic-Ischemic Neonatal Rats, Meng-Bei Zhang, Chao-Chao Song, Guang-Zu Li, Lan-Fen Chen, Rui Ma, Xiao-He Yu, Ping Gong, Xiao-Li Wang

Journal of Neurorestoratology

Objective:This study aims to observe the effects of transplantation of umbilical cord blood mononuclear cells (UCBMCs) on the expression of interleukin (IL)-1β and explore the mechanism via the toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) pathway in hypoxic-ischemic neonatal rats.Methods:Seven-day-old Sprague-Dawley neonatal rats were randomly divided into Sham, hypoxic-ischemic brain damage (HIBD), and UCBMC groups. The HIBD model was prepared by Rice-Vannucci method, and UCBMC were transplanted 24 h after HIBD in the UCBMC group. At 7 days after transplantation, changes in neurons and the TLR4 protein were examined by neuronal nuclei (NeuN)/TLR4 immunofluorescence ...


The Cell Repair Research For Parkinson’S Disease: A Systematic Review, Chao Chen, Qingfa Chen, Yan Liu, Chongyang Zhang, Kaixiang Zhu, Xue Li, Haitao Xie, Rui Zhang 2020 State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China The Institute for Tissue Engineering and Regenerative Medicine, Liaocheng People’s Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng 252004, Shangdong, China

The Cell Repair Research For Parkinson’S Disease: A Systematic Review, Chao Chen, Qingfa Chen, Yan Liu, Chongyang Zhang, Kaixiang Zhu, Xue Li, Haitao Xie, Rui Zhang

Journal of Neurorestoratology

Background and Objective:Parkinson’s disease (PD) is a common neurodegenerative disease. Previous studies have demonstrated the effect of cell-based therapies, but their clinical efficacy and safety have not been evaluated. This review protocol aimed to systematically evaluate the effect of stem cell therapy in patients with PD and to develop an evidence base for guiding policy and practice.Methods:PubMed, Embase, MedlinePlus, The Lancet and Brain were searched over the period January 2001 to October 2019. The keywords used for searching were "Parkinson’s disease" and "cell therapy" and "mesenchymal stem cells" and "embryonic stem cells" and "brain-derived neural ...


Preoperative Visualization Of Neurovascular Contact With 3d-Fiesta Combined With 3d-Tof Mra To Guide Microvascular Decompression Surgery Planning, Dezhong Liu, Pengfei Shi, Kai Li, Yazhou Guo, Xiao Liu, Changwei Wang, Yu Liu, Bing He, Xiaoyang Zhang 2020 Department of Neurosurgery, Zhoukou Central Hospital, Zhoukou 466000, Henan, China

Preoperative Visualization Of Neurovascular Contact With 3d-Fiesta Combined With 3d-Tof Mra To Guide Microvascular Decompression Surgery Planning, Dezhong Liu, Pengfei Shi, Kai Li, Yazhou Guo, Xiao Liu, Changwei Wang, Yu Liu, Bing He, Xiaoyang Zhang

Journal of Neurorestoratology

Background:Neurovascular compression syndromes including trigeminal neuralgia (TN) and hemifacial spasm (HFS) are caused by neurovascular conflicts at the root entry zone of the corresponding cranial nerves in the posterior fossa. Microvascular decompression (MVD) is the best choice for the treatment of TN and HFS. An accurate delineation of the responsible vessel could decrease the rate of possible operative complications such as nerve paresis.Methods:In this study, three-dimensional fast imaging employing steady-state acquisition (3D-FIESTA) and three-dimensional time-of-flight magnetic resonance angiography (3D-TOF MRA) were performed on 113 patients with TN or HFS. The imaging data were compared to the intraoperative ...


Oxyhemoglobin Desaturation As A Function Of Age And Hypercapnia From Ventilatory Pump Failure (Vpf), John R. Bach, Damian Pronello 2020 Physical Medicine and Rehabilitation Department of PM&R, Department of Neurology, Rutgers University New Jersey Medical School, Newark, New Jersey 07087, U.S.A.

Oxyhemoglobin Desaturation As A Function Of Age And Hypercapnia From Ventilatory Pump Failure (Vpf), John R. Bach, Damian Pronello

Journal of Neurorestoratology

Background:Supplemental O2 is often administered without knowledge of CO2 levels for patients with ventilatory pump failure (VPF). This can render oximetry ineffective as a gauge of alveolar ventilation, airway secretions, and lung disease. We have noted that diurnal hypoventilation with hypercapnia tends to be symptomatic when O2 saturation levels decrease below 95% and patients extend sleep noninvasive ventilatory support (NVS) into daytime hours. We also noted that with advancing age, less hypercapnia results in desaturation. This study was designed to explore oxyhemoglobin desaturations (O2 desats) as a function of age and hypercapnia for patients with VPF.Methods:A retrospective ...


Clinical Neurorestorative Cell Therapies: Developmental Process, Current State And Future Prospective, Hongyun Huang, Lin Chen, Gengsheng Mao, Hari Shanker Sharma 2020 Institute of Neurorestoratology, The Third Medical Centre, Chinese PLA General Hospital, Beijing 100853, China Beijing Hongtianji Neuroscience Academy, Beijing 100144, China

Clinical Neurorestorative Cell Therapies: Developmental Process, Current State And Future Prospective, Hongyun Huang, Lin Chen, Gengsheng Mao, Hari Shanker Sharma

Journal of Neurorestoratology

Clinical cell therapies (CTs) for neurological diseases and cellular damage have been explored for more than 2 decades. According to the United States Food and Drug Administration, there are 2 types of cell categories for therapy, namely stem cell-derived CT products and mature/functionally differentiated cell-derived CT products. However, regardless of the type of CT used, the majority of reports of clinical CTs from either small sample sizes based on single-center phase 1 or 2 unblinded trials or retrospective clinical studies showed effects on neurological improvement and the ability to either partially or temporarily thwart the deteriorating cellular processes of ...


Chinese Expert Consensus On Diagnosis And Management Of Split Cord Malformation, Bo Xiu, Fuyun Liu, Aijia Shang, Rui Zhang 2020 Department of Neurosurgery, The 7th Medical Center of PLA General Hospital, Beijing 100700, China

Chinese Expert Consensus On Diagnosis And Management Of Split Cord Malformation, Bo Xiu, Fuyun Liu, Aijia Shang, Rui Zhang

Journal of Neurorestoratology

Split cord malformation (SCM) is a neural tube defect that the spinal cord is longitudinally separated into two hemicords with individual functions, which causes severe spinal cord impairment and sensorimotor deficit. As a kind of myelodysplasia and a special type of tethered cord syndrome, SCM is not widely understood, and common issues in the diagnosis and treatment of SCM should be clarified. In this paper, the Chinese Split Cord Malformation Working Group made a consensus for SCM on embryopathogenesis and types, clinical presentations, neuroimaging assessment, indications and principle of the surgery, surgical techniques and nuances, and prognosis and follow up.


The 2019 Yearbook Of Neurorestoratology, Hongyun Huang, Lin Chen, Gengsheng Mao, John Bach, Qun Xue, Fabin Han, Xiaoling Guo, Ali Otom, Elena Chernykh, Edgardo Alvarez, Andrey Bryukhovetskiy, Anna Sarnowaska, Xijing He, Milan Dimitrijevic, Ihsan Shanti, Klaus von Wild, Almudena Ramón-Cueto, Ziad Alzoubi, Gustavo Moviglia, Hamid Mobasheri, Adeeb Alzoubi, Wenchuan Zhang 2020 Institute of Neurorestoratology, Third Medical Center of General Hospital of PLA, Beijing, China Cell Therapy Center, Beijing Hongtianji Neuroscience Academy, Beijing, China

The 2019 Yearbook Of Neurorestoratology, Hongyun Huang, Lin Chen, Gengsheng Mao, John Bach, Qun Xue, Fabin Han, Xiaoling Guo, Ali Otom, Elena Chernykh, Edgardo Alvarez, Andrey Bryukhovetskiy, Anna Sarnowaska, Xijing He, Milan Dimitrijevic, Ihsan Shanti, Klaus Von Wild, Almudena Ramón-Cueto, Ziad Alzoubi, Gustavo Moviglia, Hamid Mobasheri, Adeeb Alzoubi, Wenchuan Zhang

Journal of Neurorestoratology

Time is infinite movement in constant motion. We are glad to see that Neurorestoratology, a new discipline, has grown into a rich field involving many global researchers in recent years. In this 2019 yearbook of Neurorestoratology, we introduce the most recent advances and achievements in this field, including findings on the pathogenesis of neurological diseases, neurorestorative mechanisms, and clinical therapeutic achievements globally. Many patients have benefited from treatments involving cell therapies, neurostimulation/neuromodulation, brain–computer interface, neurorestorative surgery or pharmacy, and many others. Clinical physicians can refer to this yearbook with the latest knowledge and apply it to clinical practice.


Steady-State Visual Evoked Potential (Ssvep)-Based Brain–Computer Interface (Bci) Of Chinese Speller For A Patient With Amyotrophic Lateral Sclerosis: A Case Report, Nanlin Shi, Liping Wang, Yonghao Chen, Xinyi Yan, Chen Yang, Yijun Wang, Xiaorong Gao 2020 Biomedical Engineering Department, Tsinghua University, Beijing 100084, China;

Steady-State Visual Evoked Potential (Ssvep)-Based Brain–Computer Interface (Bci) Of Chinese Speller For A Patient With Amyotrophic Lateral Sclerosis: A Case Report, Nanlin Shi, Liping Wang, Yonghao Chen, Xinyi Yan, Chen Yang, Yijun Wang, Xiaorong Gao

Journal of Neurorestoratology

This study applied a steady-state visual evoked potential (SSVEP) based brain–computer interface (BCI) to a patient in lock-in state with amyotrophic lateral sclerosis (ALS) and validated its feasibility for communication. The developed calibration-free and asynchronous spelling system provided a natural and efficient communication experience for the patient, achieving a maximum free-spelling accuracy above 90% and an information transfer rate of over 22.203 bits/min. A set of standard frequency scanning and task spelling data were also acquired to evaluate the patient’s SSVEP response and to facilitate further personalized BCI design. The results demonstrated that the proposed SSVEP-based ...


State-Of-The-Art Non-Invasive Brain–Computer Interface For Neural Rehabilitation: A Review, Miaomiao Zhuang, Qingheng Wu, Feng Wan, Yong Hu 2020 Xiangya School of Medicine, Central South University, Changsha 410013, Hunan, China; Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, China

State-Of-The-Art Non-Invasive Brain–Computer Interface For Neural Rehabilitation: A Review, Miaomiao Zhuang, Qingheng Wu, Feng Wan, Yong Hu

Journal of Neurorestoratology

Brain–computer interface (BCI) is a novel communication method between brain and machine. It enables signals from the human brain to influence or control external devices. Currently, much research interest is focused on the BCI-based neural rehabilitation of patients with motor and cognitive diseases. Over the decades, BCI has become an alternative treatment for motor and cognitive rehabilitation. Previous studies demonstrated the usefulness of BCI intervention in restoring motor function and recovery of the damaged brain. Electroencephalogram (EEG)-based BCI intervention could cast light on the mechanisms underlying neuroplasticity during upper limb recovery by providing feedback to the damaged brain ...


Neurorestoration: Advances In Human Brain–Computer Interface Using Microelectrode Arrays, Jiawei Han, Hongjie Jiang, Junming Zhu 2020 Department of Neurosurgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Zhejiang University, Hangzhou 310058, China

Neurorestoration: Advances In Human Brain–Computer Interface Using Microelectrode Arrays, Jiawei Han, Hongjie Jiang, Junming Zhu

Journal of Neurorestoratology

Neural damage has been a great challenge to the medical field for a very long time. The emergence of brain–computer interfaces (BCIs) offered a new possibility to enhance the activity of daily living and provide a new formation of entertainment for those with disabilities. Intracortical BCIs, which require the implantation of microelectrodes, can receive neuronal signals with a high spatial and temporal resolution from the individual’s cortex. When BCI decoded cortical signals and mapped them to external devices, it displayed the ability not only to replace part of the human motor function but also to help individuals restore ...


Correlation Between Programmed Stimulation Parameters And Their Efficacy After Deep Brain Electrode Implantation For Parkinson’S Disease, Jingchao Lu, Zhaohai Feng, Xin Shi, Lei Jiang, Yujun Hao 2020 Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang, China

Correlation Between Programmed Stimulation Parameters And Their Efficacy After Deep Brain Electrode Implantation For Parkinson’S Disease, Jingchao Lu, Zhaohai Feng, Xin Shi, Lei Jiang, Yujun Hao

Journal of Neurorestoratology

Purpose:Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an indispensable and effective surgery for patients with primary Parkinson’s disease (PD). Nonetheless, its postoperative effects can be decided by many factors including the optimal programmed stimulation parameters. In this study, we analyzed the correlation between different postoperative programmed stimulation parameters and their efficacy after STN–DBS electrode implantation in patients with PD.Methods:A total of 87 patients underwent electrode implantation and completed at least one year follow-up. Then, various combinations of stimulation parameters, including stimulus intensity, frequency, and pulse width, were examined for their effects on ...


Brain Gamma Rhythm And Potential Treatment Of Neurodegenerative Disease, Jianhua Zhao, Ailin Du, Chengbiao Lu 2020 Department of Neurology, First Affiliated Hospital of Xinxiang Medical University, Weihui 453100, Henan, China; Henan Joint International Research Laboratory of Neurorestoratology for Senile Dementia / Henan Key Laboratory of Neurorestoratology, Weihui 453100, Henan, China;

Brain Gamma Rhythm And Potential Treatment Of Neurodegenerative Disease, Jianhua Zhao, Ailin Du, Chengbiao Lu

Journal of Neurorestoratology

In this mini-review, we illustrate the brain network oscillations in different brain areas, including the medial septal diagonal band complex (MSDB) and hippocampus, especially at gamma frequency bands (γ, 30–80 Hz) and theta frequency bands (θ, 4–12 Hz), and their induction and modulation by physical stimulation, such as light and sound, and pharmacological stimulation with agents such as agonists of the kainite subunit ionotropic glutamate receptor, metabotropic glutamate receptor, metabotropic cholinergic receptor, and nicotinic cholinergic receptor. Recent findings demonstrate that boosting gamma oscillations in specific brain areas appears to be able to restore cognitive function and reduce relative ...


Traditional Chinese Medicine-Based Neurorestorative Therapy For Alzheimer’S And Parkinson’S Disease, Zhu Zhang, Shiqing Zhang, Cathy Nga-Ping Lui, Peili Zhu, Zhang Zhang, Kaili Lin, Yiwu Dai, Ken Kin-Lam Yung 2020 Department of Biology, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China Golden Meditech Center for NeuroRegeneration Sciences (GMCNS), Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China

Traditional Chinese Medicine-Based Neurorestorative Therapy For Alzheimer’S And Parkinson’S Disease, Zhu Zhang, Shiqing Zhang, Cathy Nga-Ping Lui, Peili Zhu, Zhang Zhang, Kaili Lin, Yiwu Dai, Ken Kin-Lam Yung

Journal of Neurorestoratology

The prevalence of multiple neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), has been dramatically increasing, particularly in the aging population. However, the currently available therapies merely alleviate the symptoms of these diseases and are unable to retard disease progression significantly. Traditional Chinese medicine (TCM) has been used in clinical practice for thousands of years for ameliorating symptoms or interfering with the pathogenesis of aging- associated diseases. Modern pharmacological studies have proved that TCM imparts disease-modifying therapeutic effects against these diseases, such as protection of neurons, clearance of protein aggregates, and regulation of neuroinflammation. This ...


Small Ruptured And Unruptured Complex Cerebral Aneurysms: Single Center Experience Of Low-Profile Visualized Intraluminal Support Stent, Xianli Lv, Chuhan Jiang, Shikai Liang 2020 Department of Neurosurgery, School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China

Small Ruptured And Unruptured Complex Cerebral Aneurysms: Single Center Experience Of Low-Profile Visualized Intraluminal Support Stent, Xianli Lv, Chuhan Jiang, Shikai Liang

Journal of Neurorestoratology

Objectives:Even though low-profile visualized intraluminal support (LVIS) device is used extensively currently and provide intraluminal support in complex cerebral aneurysm embolization, only few studies have reported its clinical results. This study presents the results of patients treated with LVIS.Patients and methods:Cerebral aneurysms with an undefined neck, fusiform shape, and blood blister-like aneurysms that were treated with LVIS between May 2017 and May 2019 were reviewed retrospectively.Results:Overall, 112 aneurysms in 104 patients were treated using LVIS, and 105 LVISs were placed. Of these, 101 aneurysms (90%) were small (< 10 mm) in size, 17 were fusiform aneurysms, and 3 were blood blister-like aneurysms. Overall, 39 patients suffered a subarachnoid hemorrhage and 65 had no bleeding history. 2 patients died of internal carotid artery (ICA) thrombosis, resulting in 1.9% mortality rate. Follow-up angiography was obtained in 68 patients (65%), and the complete obliteration rate was 98.5% in 6–12 months.Conclusion:The LVIS is a safe and effective treatment for small ruptured or unruptured complex intracranial aneurysms.


Research And Application Progress On Dural Substitutes, Weizuo Wang, Qiang Ao 2020 Department of Tissue Engineering, China Medical University, Shenyang 110122, Liaoning, China

Research And Application Progress On Dural Substitutes, Weizuo Wang, Qiang Ao

Journal of Neurorestoratology

Dural defects are a common problem in clinical practice, and various types of dural substitutes have been used to deal with dural defects. These play an important role in dural repair. Dural substitutes have gradually reached researchers, neurosurgeons, and patients for approval. This article summarizes the structural characteristics of the dura mater and its regeneration after injury, and reviews the state of progress in research and application. It will provide a reference for the development and application of dural substitutes.


Progress In Research Into Spinal Cord Injury Repair: Tissue Engineering Scaffolds And Cell Transdifferentiation, Changke Ma, Peng Zhang, Yixin Shen 2020 Department of Orthopaedics, The People's Hospital of Luhe, Nanjing 211500, Jiangsu, China

Progress In Research Into Spinal Cord Injury Repair: Tissue Engineering Scaffolds And Cell Transdifferentiation, Changke Ma, Peng Zhang, Yixin Shen

Journal of Neurorestoratology

As with all tissues of the central nervous system, the low regeneration ability of spinal cord tissue after injury decreases the potential for repair and recovery. Initially, in spinal cord injuries (SCI), often the surgeon can only limit further damage by early surgical decompression. However, with the development of basic science, especially the development of genetic engineering, molecular biology, tissue engineering, and materials science, some promising progress has been made in promoting the repair of central nervous system injuries. For example, transplantation of neural stem cells (NSCs), olfactory ensheathing cells (OECs), and gene- mediated transdifferentiation to repair central nervous system ...


Lateralized Spontaneous Exploratory Behavior In Maturing Rats Induced By New Geometrically Differentiated Environments After Administration With Trace Elements, Silvia G. Ratti, Osvaldo J. Sacchi, Edgardo O. Alvarez 2020 Laboratorio de Neuropsicofarmacología Experimental, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina

Lateralized Spontaneous Exploratory Behavior In Maturing Rats Induced By New Geometrically Differentiated Environments After Administration With Trace Elements, Silvia G. Ratti, Osvaldo J. Sacchi, Edgardo O. Alvarez

Journal of Neurorestoratology

Functional laterality is known as an intrinsic property of the brain. Since several studies have shown the presence of laterality in many species other than humans, it has been suggested that this is an adaptive mechanism to aid survival. Previous studies have shown that lateralized behavior observed during exposure to different environmental stimuli is not constant in normal animals, depending on the geometrical form of the exploratory field. In these exploratory fields, animals showed right- or left-biased exploratory behavior, according to the nature of the geometrical properties of the environment. Previously, it was found that tellurium (Te) was able to ...


Cerebral Small Vessel Disease And Cognitive Impairment, Lifang Meng, Jianhua Zhao, Junli Liu, Shaomin Li 2020 First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, China Henan Key Laboratory of Neurorestoratology, Xinxiang 453100, Henan,China Henan Joint International Research Laboratory of Neurorestoratology for Senile Dementia, Xinxiang 453100, Henan, China

Cerebral Small Vessel Disease And Cognitive Impairment, Lifang Meng, Jianhua Zhao, Junli Liu, Shaomin Li

Journal of Neurorestoratology

Cerebral small vessel disease (CSVD) is a pathophysiological process involving small arteries such as cerebellar arteries, arterioles, capillaries, and veinlets. Imaging features vary; they are mainly composed of recent subcortical infarcts, lacunes of presumed vascular origin, white matter hyperintensities (WMHs) of presumed vascular origin, cerebral microbleeds, enlarged perivascular spaces, and global and regional brain atrophy. CSVD is a common cause of vascular cognitive dysfunction, and in its end stage, dementia often develops. CSVD has been a major research hotspot; however, its causes are poorly understood. Neuroimaging markers of CSVD can be used as the basis for etiological analysis. This review ...


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